{"id":2883,"date":"2026-02-14T08:09:24","date_gmt":"2026-02-14T08:09:24","guid":{"rendered":"https:\/\/whmnews.ir\/En\/?p=2883"},"modified":"2026-02-14T08:10:15","modified_gmt":"2026-02-14T08:10:15","slug":"experimental-drug-improves-survival-in-deadly-cancer","status":"publish","type":"post","link":"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/","title":{"rendered":"Experimental drug improves survival in deadly cancer"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Experimental drug improves survival in deadly cancer<\/strong><\/p>\n<p style=\"text-align: justify;\">Patients with one of the deadliest gynecological cancers had dramatically improved survival when an experimental drug was added to treatment with a standard chemotherapy medication in a mid-stage trial in Belarus, researchers say.<\/p>\n<p style=\"text-align: justify;\">The 30 women in the study had ovarian cancer resistant to first-line platinum-based chemo drugs, along with elevated blood levels of a cancer protein called CA-125.<\/p>\n<p style=\"text-align: justify;\">All received standard gemcitabine chemotherapy, and half also received elenagen, being developed by CureLab Oncology, as a once-weekly injection into the muscle.<\/p>\n<p style=\"text-align: justify;\">Patients in the elenagen group lived significantly longer, with a median survival of more than 25 months, compared to roughly 13 months with gemcitabine alone.<\/p>\n<p style=\"text-align: justify;\">\u201cSeveral patients survived years beyond expected survival for this disease setting,\u201d the researchers said in a statement.<\/p>\n<p style=\"text-align: justify;\">Treatment with elenagen also reduced mortality risk by nearly 60%, the researchers found.<\/p>\n<p style=\"text-align: justify;\">\u201cWhat makes these results remarkable is not only the magnitude of the survival benefit, but that it was achieved without added toxicity and without a specific biomarker,\u201d study leader Dr. Sergei Krasny of the N. N. Alexandrov National Cancer Centre of Belarus in Minsk said in a statement.<\/p>\n<p style=\"text-align: justify;\">Elenagen contains a protein called p62\/SQSTM1 that reduces chronic inflammation and triggers an immune response against tumors.<\/p>\n<p style=\"text-align: justify;\">The drug&#8217;s effect points to the value of &#8220;a fundamentally different therapeutic approach, one that supports the body&#8217;s biology rather than simply intensifying chemotherapy,\u201d Krasny said.<\/p>\n<p style=\"text-align: justify;\">Treatment intervals ranged from less than one month to more than 30 months, with longer duration of treatment strongly correlated with longer survival following treatment discontinuation, they also found.<\/p>\n<p style=\"text-align: justify;\">The company said it is planning to conduct larger trials in the U.S.<\/p>\n<p style=\"text-align: justify;\">Details from the trial were published in the International Journal of Gynecologic Cancer and will be presented on February 27 at the European Society of Gynaecological Oncology meeting in Copenhagen.<\/p>\n<p style=\"text-align: justify;\">\n","protected":false},"excerpt":{"rendered":"<p>Experimental drug improves survival in deadly cancer Patients with one of the deadliest gynecological cancers had dramatically improved survival when an experimental drug was added to treatment with a standard chemotherapy medication in a mid-stage trial in Belarus, researchers say. The 30 women in the study had ovarian cancer resistant to first-line platinum-based chemo drugs, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":2884,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[955],"class_list":["post-2883","post","type-post","status-publish","format-standard","has-post-thumbnail","category-pharmaceutical-scientific-articles","tag-experimental-drug-improves-survival-in-deadly-cancer"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.1 (Yoast SEO v24.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Experimental drug improves survival in deadly cancer - whmnews<\/title>\n<meta name=\"description\" content=\"Experimental drug improves survival in deadly cancer\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Experimental drug improves survival in deadly cancer\" \/>\n<meta property=\"og:description\" content=\"Experimental drug improves survival in deadly cancer\" \/>\n<meta property=\"og:url\" content=\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"whmnews\" \/>\n<meta property=\"article:published_time\" content=\"2026-02-14T08:09:24+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-14T08:10:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/whmnews.ir\/En\/wp-content\/uploads\/2026\/02\/Experimental-drug-improves-survival-in-deadly-cancer.png\" \/>\n\t<meta property=\"og:image:width\" content=\"641\" \/>\n\t<meta property=\"og:image:height\" content=\"360\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Roza News\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Roza News\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/\"},\"author\":{\"name\":\"Roza News\",\"@id\":\"https:\/\/whmnews.ir\/En\/#\/schema\/person\/77fef232f03e0a43eb2c2ecc12e4de2e\"},\"headline\":\"Experimental drug improves survival in deadly cancer\",\"datePublished\":\"2026-02-14T08:09:24+00:00\",\"dateModified\":\"2026-02-14T08:10:15+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/\"},\"wordCount\":311,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/whmnews.ir\/En\/#organization\"},\"image\":{\"@id\":\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/whmnews.ir\/En\/wp-content\/uploads\/2026\/02\/Experimental-drug-improves-survival-in-deadly-cancer.png\",\"keywords\":[\"Experimental drug improves survival in deadly cancer\"],\"articleSection\":[\"Pharmaceutical Scientific Articles\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/\",\"url\":\"https:\/\/whmnews.ir\/En\/index.php\/2026\/02\/14\/experimental-drug-improves-survival-in-deadly-cancer\/\",\"name\":\"Experimental drug improves survival in deadly cancer - 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