{"id":3000,"date":"2026-10-08T07:35:28","date_gmt":"2026-10-08T07:35:28","guid":{"rendered":"https:\/\/whmnews.ir\/En\/?p=3000"},"modified":"2026-10-08T07:36:52","modified_gmt":"2026-10-08T07:36:52","slug":"experimental-approach-uses-ai-to-eliminate-cold-storage-for-mrna-vaccines","status":"publish","type":"post","link":"https:\/\/whmnews.ir\/En\/index.php\/2026\/10\/08\/experimental-approach-uses-ai-to-eliminate-cold-storage-for-mrna-vaccines\/","title":{"rendered":"Experimental approach uses AI to eliminate cold storage for mRNA vaccines"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Experimental approach uses AI to eliminate cold storage for mRNA vaccines<\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>TEMPERATURE STORAGE OF MRNA VACCINES MAY BE NEAR<\/strong><br \/>\nUsing artificial intelligence, researchers may have found a way to make vaccines based \u200con mRNA technology, such as Moderna&#8217;s (MRNA.O), opens new tab and Pfizer&#8217;s (PFE.N), opens new tab COVID shots, storable at room temperature, which would lower costs and make them available in regions where ultra-cold storage is not possible.<\/p>\n<p style=\"text-align: justify;\">Presently, mRNA vaccines, including Moderna&#8217;s new flu shot, must be stored at extremely low temperatures, typically ranging from -40 to -123 degrees Fahrenheit (-40 to -86 Celsius).<br \/>\nThat is because messenger RNA is extremely fragile and breaks down easily at higher temperatures.<br \/>\nWith help from artificial intelligence, researchers tweaked the formulation of the lipid nanoparticles that carry the mRNA in the vaccines, making the particles more heat-resistant.<br \/>\nUsing this \u200bapproach, they formulated vaccines that could remain stable even when stored at room temperature for up to a year, or at nearly 100 degrees Fahrenheit for two months, according to a report published in Nature \u200bBiotechnology, opens new tab.<\/p>\n<p style=\"text-align: justify;\">Mice that were vaccinated with these particles, even after long-term storage, showed equivalent immune responses to mice that received vaccines carried by lipid nanoparticles similar to the original formulation \u2060used by Moderna.<\/p>\n<p style=\"text-align: justify;\">\u201cCold-chain requirements add considerable infrastructure costs throughout the product life cycle, including specialized packaging, ultra-cold storage, temperature-controlled transport and continuous monitoring,\u201d the researchers noted in their report.<br \/>\nVaccines that tolerate higher temperatures could reduce storage costs by \u200bup to 86%, they added.<br \/>\n\u201cOur approach broadens the application of not only mRNA vaccines, but also therapeutics or advanced drug-delivery platforms like controlled-release particles or microneedle patches, which requires the formulation to either be in solid state or to \u200bbe stable at higher temperature,\u201d study leader Jinbi Tian of MIT said in a statement.<\/p>\n<p style=\"text-align: justify;\">\n","protected":false},"excerpt":{"rendered":"<p>Experimental approach uses AI to eliminate cold storage for mRNA vaccines TEMPERATURE STORAGE OF MRNA VACCINES MAY BE NEAR Using artificial intelligence, researchers may have found a way to make vaccines based \u200con mRNA technology, such as Moderna&#8217;s (MRNA.O), opens new tab and Pfizer&#8217;s (PFE.N), opens new tab COVID shots, storable at room temperature, which [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":3003,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[990],"class_list":["post-3000","post","type-post","status-publish","format-standard","has-post-thumbnail","category-technology-health","tag-experimental-approach-uses-ai-to-eliminate-cold-storage-for-mrna-vaccines"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.1 (Yoast SEO v24.1) - 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